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Genes are responsible for the control of inheritance in all organisms. The abnormal or mutated genes and their products are responsible for several inherited eye diseases such as cataracts, glaucoma, retinal degenerations, corneal abnormalities, etc. Recent studies have shown that abnormal gene interactions are also responsible for several common eye diseases such as age related cataract, age related macular degenerations, etc. The department aims to study abnormal gene interactions and mutated genes of eye diseases such as pediatric cataract, pediatric glaucoma, age related cataract, age related macular degeneration, etc. The department is equipped with PCR, UV-visible spectrophotometer, gel electrophoresis systems, centrifuges, real time PCR etc. For further studies department requires certain modern equipments such as DNA sequencers, set up for fluorescence in situ hybridization (FISH), etc. The centre was a part of multicentric study for identifying mutations in congenital cataracts. The project was funded by CSIR . We are also focusing on finding single nucleotide polymorphisms (SNP's) in crystallin genes and allelic frequencies of the same in cataractous patients.
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